Evaluating Inhalation Safety of Fragrances

Fragrances are intended to be enjoyed through the sense of smell. Therefore, one primary route of exposure to fragrance materials is inhalation. The Research Institute for Fragrance Materials (RIFM) has an active scientific program to verify the inhalation safety of fragrance materials. With a multi faceted approach, RIFM has established projects to identify parameters of sensitization, estimate potential physiological fate and effects using a computational fluid dynamics model, and calculate air concentrations to determine potential inhalation exposure based on human ventilation. Within this comprehensive program, RIFM has also taken the initiative to develop alternative research methods. The Respiratory Sciences Program at RIFM is designed to further support the safe use of fragrances.

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