Publications

Publications


 

Application of the expanded Creme RIFM consumer exposure model to fragrance ingredients in cosmetic, personal care and air care products


Application of the expanded Creme RIFM consumer exposure model to fragrance ingredients in cosmetic, personal care and air care products
Regulatory Toxicology and Pharmacology
Volume 86, June 2017, Pages 148–156

Highlights

The Creme RIFM model is a comprehensive tool for estimating aggregate exposure.

Consumer data based on 25 product types by over 37,000 subjects provide the backbone.

Data were collated from 33 fragrance houses and 10 manufacturers of products.

Highest fragrance exposure occurred from body lotions, body sprays and perfumes.

The model suggests that deterministic models overestimate exposure by 11.5–25 fold.