# RIFM

> The Research Institute for Fragrance Materials \(RIFM\) provides a scientific basis for fragrance safety and the safe use of fragrance for the protection of consumers and the environment\.

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## Pages
- [Member Benefits](https://rifm.org/member-benefits/)
- [Member Home Rev 061126](https://rifm.org/member-home-rev/)
- [RIFM High Dose Human Relevance \- Trade Journal Articles](https://rifm.org/high-dose-human-relevance-trade-journal-articles/)
- [RIFM High Dose Human Relevance \- Videos](https://rifm.org/high-dose-human-relevance-videos/)
- [RIFM High Dose Human Relevance \- Ask a RIFM Scientist](https://rifm.org/high-dose-human-relevance-ask-a-rifm-scientist/)

## Posts
- [REGISTER NOW: RIFM's 60th Annual Meeting\!](https://rifm.org/save-the-date-rifms-60th-annual-meeting/)
- [RIFM Advances Non\-Animal Safety Assessment Science at ESTIV 2026 with Three Expert Contributions ](https://rifm.org/rifm-advances-non-animal-safety-assessment-science-at-estiv-2026-with-three-expert-contributions/)
- [RECORDING \& SLIDES NOW AVAILABLE: From High\-Dose Studies to Human Relevance: Understanding Fragrance Safety](https://rifm.org/from-high-dose-studies-to-human-relevance-understanding-fragrance-safety/)
- [RIFM Research Highlights Advances in Skin Sensitization Science at ESCD 2026](https://rifm.org/rifm-research-highlights-advances-in-skin-sensitization-science-at-escd-2026/)
- [RIFM Consumer Product Survey 2026 – Data Request for 10 Product Categories](https://rifm.org/rifm-consumer-product-survey-2026-data-request-for-10-product-categories/)

## Callouts
- [Member Benefits](https://rifm.org/callout/member-benefits/)
- [Safety Assessment Program](https://rifm.org/callout/safety-assessment-program/)
- [RIFM Research](https://rifm.org/callout/rifm-research/)
- [RIFM Database](https://rifm.org/callout/rifm-database/)
- [Expert Panel](https://rifm.org/callout/expert-panel/)

## Publications
- [Aquatic risk of fragrance materials: advancing prioritization in aquatic systems](https://rifm.org/publication/aquatic-risk-of-fragrance-materials-advancing-prioritization-in-aquatic-systems/)
- [Advancing chemical grouping: development and application of signature\-based structure\-activity groups for non\-animal safety assessments](https://rifm.org/publication/advancing-chemical-grouping-development-and-application-of-signature-based-structure-activity-groups-for-non-animal-safety-assessments/)
- [The Chicken Egg Genotoxicity Assay \(CEGA\): Assessing Target Tissue Exposure and Metabolism in the Embryo\-Fetal Chicken Livers](https://rifm.org/publication/the-chicken-egg-genotoxicity-assay-cega-assessing-target-tissue-exposure-and-metabolism-in-the-embryo-fetal-chicken-livers/)
- [Responses of an In Vitro Coculture Alveolar Model for the Prediction of Respiratory Sensitizers \(ALIsens®\) Following Exposure to Skin Sensitizers and Non\-Sensitizers](https://rifm.org/publication/responses-of-an-in-vitro-coculture-alveolar-model-for-the-prediction-of-respiratory-sensitizers-alisens-following-exposure-to-skin-sensitizers-and-non-sensitizers/)
- [Detailed aggregate exposure analysis shows that exposure to fragrance ingredients in consumer products is low: Many orders of magnitude below thresholds of concern](https://rifm.org/publication/detailed-aggregate-exposure-analysis-shows-that-exposure-to-fragrance-ingredients-in-consumer-products-is-low-many-orders-of-magnitude-below-thresholds-of-concern/)

## Board of Directors
- [Catherine Gadras, PhD](https://rifm.org/directors/catherine-gadras-phd/)
- [Veronique Scailteur, PhD \(Secretary\)](https://rifm.org/directors/veronique-scailteur-phd/)
- [Christopher Choi, PhD, DABT, ERT \(Treasurer\)](https://rifm.org/directors/christopher-choi-phd-dabt-ert/)
- [Susanne Kettler \(Vice Chair\)](https://rifm.org/directors/susanne-kettler/)
- [Ron Stark \(Chair\)](https://rifm.org/directors/ron-stark/)

## Careers
- [test](https://rifm.org/career/test/)
- [Lorem ipsum](https://rifm.org/career/lorem-ipsum/)
- [Position Title](https://rifm.org/career/position-title/)

## Questions
- [If a study shows a fragrance ingredient can cause "adverse effects" in a lab, why is it still considered safe for me to use in my daily products?](https://rifm.org/question/if-a-study-shows-a-fragrance-ingredient-can-cause-adverse-effects-in-a-lab-why-is-it-still-considered-safe-for-me-to-use-in-my-daily-products/)
- [How does RIFM assess respiratory safety for fragranced products?](https://rifm.org/question/how-does-rifm-assess-respiratory-safety-for-fragranced-products/)
- [Do safety assessments ever change?](https://rifm.org/question/do-safety-assessments-ever-change/)
- [How does RIFM assess the safety of natural fragrance ingredients?](https://rifm.org/question/how-does-rifm-assess-the-safety-of-natural-fragrance-ingredients/)
- [What does the Creme RIFM Model tell us about fragrance exposure?](https://rifm.org/question/what-does-the-creme-rifm-model-tell-us-about-fragrance-exposure/)

## Agenda and Minutes
- [Agenda and Minutes April 7, 2026](https://rifm.org/agenda-minutes/agenda-and-minutes-april-7-2026/)
- [Agenda and Minutes March 1, 2026](https://rifm.org/agenda-minutes/agenda-and-minutes-march-1-2026/)
- [Agenda and Minutes December 1, 2025](https://rifm.org/agenda-minutes/agenda-and-minutes-december-1-2025/)
- [Agenda and Minutes January 23, 2026](https://rifm.org/agenda-minutes/january-23-2026/)
- [Agenda and Minutes February 9, 2026](https://rifm.org/agenda-minutes/agenda-and-minutes-february-9-2026/)

## Documents
- [Update to 4\-methyl\-3\-penten\-2\-one \(CAS \# 141\-79\-7\)](https://rifm.org/documents/update-to-4-methyl-3-penten-2-one-cas-141-79-7/)
- [Update to 2\-acetylthiazole \(CAS \# 24295\-03\-2\)](https://rifm.org/documents/update-to-2-acetylthiazole-cas-24295-03-2/)
- [Update to hexyl 2\-hydroxypropionate \(CAS \# 20279\-51\-0\)](https://rifm.org/documents/update-to-hexyl-2-hydroxypropionate-cas-20279-51-0/)
- [Q2 2026 Running list of NS candidates \(July 1, 2026\)](https://rifm.org/documents/q2-2026-running-list-of-ns-candidates-july-1-2026/)
- [Final 2025 Not Supported List \(version 3, July 1, 2026\)](https://rifm.org/documents/final-2025-not-supported-list-version-3-july-1-2026/)

## RIFM Teams
- [Advisory Committee](https://rifm.org/rifm-teams/advisory-committee/)
- [Respiratory](https://rifm.org/rifm-teams/respiratory/)
- [Phototoxicity/Photoallergy](https://rifm.org/rifm-teams/phototoxicity-photoallergy/)
- [Repeated Dose and Reproductive](https://rifm.org/rifm-teams/repeated-dose-and-reproductive/)
- [Environmental](https://rifm.org/rifm-teams/environmental/)

## Organizations
- [Yves Rocher](https://rifm.org/organization/yves-rocher/)
- [Yinghai \(Cangzhou\) Aroma Chemical Co\. Ltd\.](https://rifm.org/organization/yinghai-cangzhou-aroma-chemical-co-ltd/)
- [Yankee Candle Company, A Subsidiary of Newell Brands](https://rifm.org/organization/yankee-candle-company-a-subsidiary-of-newell-brands/)
- [Wrigley](https://rifm.org/organization/wrigley/)
- [Wrigley Confectionery Ltd\.](https://rifm.org/organization/wrigley-confectionery-ltd/)

## Lessons
- [Lesson 1: History of Fragrance Safety Science](https://rifm.org/lesson/lesson1-history-of-fragrance-safety-science/)
- [New Lesson](https://rifm.org/lesson/new-lesson/)
- [New Lesson](https://rifm.org/lesson/new-lesson-3/)
- [New Lesson](https://rifm.org/lesson/new-lesson-2/)
- [Lesson 1: Anatomy of a RIFM assessment](https://rifm.org/lesson/lesson1-anatomy-of-a-rifm-assessment/)

## Quizzes
- [Lesson 1: History of Fragrance Safety Science Quiz](https://rifm.org/quiz/lesson-1-history-of-fragrance-safety-science-quiz/)

## Tags
- [Fragrance safety](https://rifm.org/tag/fragrance-safety/)
- [RIFM](https://rifm.org/tag/rifm/)
- [skin sensitization](https://rifm.org/tag/skin-sensitization/)
- [Chemistry](https://rifm.org/tag/chemistry/)
- [Clustering](https://rifm.org/tag/clustering/)

## Teams
- [Skin Sensitization](https://rifm.org/team/skin-sensitization/)
- [Aggregate Exposure](https://rifm.org/team/aggregate-exposure/)
- [Respiratory](https://rifm.org/team/respiratory/)
- [Repeated Dose](https://rifm.org/team/repeated-dose/)
- [Reproductive](https://rifm.org/team/reproductive/)

## Teams
- [Directors](https://rifm.org/directors-team/directors-team/)
- [Executive Committee](https://rifm.org/directors-team/executive-committee/)
- [Nonvoting Liaison Guests](https://rifm.org/directors-team/nonvoting-liaison-guests/)
- [General Counsel](https://rifm.org/directors-team/general-counsel/)

## Scientists
- [Anne Marie Api, PhD, Fellow ATS](https://rifm.org/scientists/anne-marie-api/)
- [Danielle Botelho, PhD](https://rifm.org/scientists/danielle-botelho/)
- [Kaushal Joshi, PhD, DABT](https://rifm.org/scientists/kaushal-joshi/)
- [Nikaeta Sadekar, PhD, DABT](https://rifm.org/scientists/nikaeta-sadekar/)
- [Holger Moustakas, PhD](https://rifm.org/scientists/holger-moustakas-phd/)

## Categories
- [Science Documents](https://rifm.org/document-categories/science-documents/)
- [Safety Assessments](https://rifm.org/document-categories/safety-assessments/)
- [Board Documents](https://rifm.org/document-categories/board-documents/)
- [April 8, 2025](https://rifm.org/document-categories/april-8-2025/)
- [June 11, 2024](https://rifm.org/document-categories/june-11-2024/)

## Optional
- [Sitemap index](https://rifm.org/sitemap_index.xml)