Advancing Fragrance Safety at SOT: Holger Moustakas, PhD, presents on read-across
Later this month, several RIFM scientists will join over 5,000 toxicologists participating in more than 70 scientific sessions and offer over 2,000 poster presentations at the Society of Toxicology (SOT) 62nd Annual Meeting.
During the event, Holger Moustakas, PhD, Senior Scientist, Chemistry & Genotoxicity, will present on a collaboration between RIFM scientists and members of the Expert Panel for Fragrance Safety, An End Point-Specific Framework for Read-Across Analog Selection for Human Health Effects, which was peer-reviewed and published last year in Chemical Research and Toxicology. (Download the paper here.)
Dr. Moustakas will present as part of the Computational Toxicology I session beginning at 2:30 PM on March 20th.
Read-across is a safety assessment approach in which scientists can use study data on one chemical as a proxy to support the safe use of a toxicologically similar chemical lacking study data.
Dr. Moustakas discussed the paper’s importance and impact in a recent Ask a RIFM Scientist post. “Endpoint specificity in read-across analog selection makes read-across a more scientific process,” he explained. “In addition, it expands the potential read-across options RIFM scientists have, which allows them to ensure the safety of more fragrance ingredients while avoiding extra testing and saving animal lives.”