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Forceps probing a bright flower held by a hand in a medical glove

RIFM showcases next-generation risk assessment at WC13 lunch session

8.22.25

At the 13th World Congress on Alternatives and Animal Use in the Life Sciences (WC13) in Rio de Janeiro, the Research Institute for Fragrance Materials (RIFM) will host a special Lunch Session highlighting advances in fragrance safety science.

Session 119: Next-Generation Risk Assessment for Fragrance Materials
Tuesday, September 2, 13:15–14:15

Chaired by RIFM President Anne Marie Api, PhD, Fellow ATS, the session brings together four RIFM scientists to present the Institute’s latest work on advancing the safety evaluation of fragrance ingredients, a process rooted in the peer-reviewed literature (see Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) Safety Evaluation Process for Fragrance Ingredients and The RIFM Approach to Evaluating Natural Complex Substances (NCS)).

The program includes:

  • RIFM Director of Scientific Operations Danielle Botelho, PhD – Advancing Next-Generation Risk Assessment for Fragrance Materials
  • RIFM President Anne Marie Api, PhD, Fellow ATS – The Critical Role of Exposure Data in Fragrance Safety Assessment
  • RIFM Senior Associate Scientist Isabella Schember, PhD – The Maximum Acceptable Concentration Process and the Role of Quantitative Risk Assessment 2
  • RIFM Principal Scientist Aurelia Lapczynski – Environmental Risk Assessment of Fragrance Materials—Expanding Region-Specific Frameworks

The one-hour session will provide an interactive overview of RIFM’s comprehensive approach, which integrates human health and environmental exposure, read-across strategies, and measured exposure data. The discussion will also explore how New Approach Methodologies (NAMs) are shaping the future of fragrance safety, aligned with the 3Rs principle at the heart of WC13: Integrating Human, Animal, and Environmental Health.

“RIFM is committed to advancing science-based, non-animal methods that both ensure safety and foster innovation,” Dr. Api said. “Measured exposure data and robust models fully inform how we assess fragrance ingredients; we do not perform animal testing for any of our human health endpoints.”

“At RIFM, we’ve built a trusted legacy of ensuring fragrance safety by combining cutting-edge science with global collaboration,” Dr. Botelho affirmed. “I’m excited to share at WC13 how our comprehensive approach—integrating exposure data, read-across, and New Approach Methodologies—is shaping the future of fragrance safety for both people and the environment.”

With presentations designed to engage both newcomers and seasoned safety assessors, this Lunch Session underscores RIFM’s commitment to advancing trusted science while ensuring the safe use of fragrance materials worldwide.

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8.22.25
RIFM showcases next-generation risk assessment at WC13 lunch session

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